| 2024-02 |
Cost and time-efficient construction of a 3′-end mRNA library from unpurified bulk RNA in a single tube |
Experimental & Molecular Medicine
|
| 2024-02 |
An open-source, 3D printed inkjet DNA synthesizer |
Scientific Reports
|
| 2023-11 |
Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection |
Experimental and Molecular Medicine
|
| 2023-11 |
Globally shared TCR repertoires within the tumor-infiltrating lymphocytes of patients with metastatic gynecologic cancer |
Scientific Reports
|
| 2023-08 |
Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer |
British Journal of Cancer
|
| 2023-07 |
Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA |
Cancer Research and Treatment
|
| 2023-05 |
Accurate Detection of Urothelial Bladder Cancer Using Targeted Deep Sequencing of Urine DNA |
Cancers
|
| 2023-05 |
Practical Utility of Liquid Biopsies for Evaluating Genomic Alterations in Castration-Resistant Prostate Cancer |
Cancers
|
| 2023-03 |
EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution |
Clinical Epigenetics
|
| 2022-12 |
Onepot-Seq: capturing single-cell transcriptomes simultaneously in a continuous medium via transient localization of mRNA |
Nucleic acids research
|
| 2022-11 |
Differentially hypomethylated cell-free DNA and coronary collateral circulation |
Clinical Epigenetics
|
| 2022-09 |
Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment |
British Journal of Cancer
|
| 2021-10 |
Engineered Attenuated Salmonella typhimurium Expressing Neoantigen Has Anticancer Effects |
ACS SYNTHETIC BIOLOGY
|
| 2021-08 |
Novel somatic variants involved in biochemical activity of pure growth hormone-secreting pituitary adenoma without GNAS variant |
SCIENTIFIC REPORTS
|
| 2021-07 |
Introduction to single-cell dna methylation profiling methods |
Biomolecules
|
| 2021-06 |
Accurate Detection of Rare Mutant Alleles by Target Base-Specific Cleavage with the CRISPR/Cas9 System |
ACS SYNTHETIC BIOLOGY
|
| 2020-05 |
Multiplex Generation, Tracking, and Functional Screening of Substitution Mutants Using a CRISPR/Retron System |
ACS SYNTHETIC BIOLOGY
|
| 2020-05 |
MAPS-seq: magnetic bead-assisted parallel single-cell gene expression profiling |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2020-05 |
Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing |
PLOS ONE
|
| 2020-04 |
Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells |
COMMUNICATIONS BIOLOGY
|
| 2020-03 |
Promiscuous Trans-splicing Activities Revealed by Next Generation Sequencing-based Analysis of 298 Split Inteins |
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
|
| 2019-10 |
Tumor Mutation Burden and Prognosis in Patients with Colorectal Cancer Treated with Adjuvant Fluoropyrimidine and Oxaliplatin |
CLINICAL CANCER RESEARCH
|
| 2019-05 |
Association of pathway mutation with survival after recurrence in colorectal cancer patients treated with adjuvant fluoropyrimidine and oxaliplatin chemotherapy |
BMC CANCER
|
| 2019-05 |
Multiplexed single-cell RNA-seq via transient barcoding for simultaneous expression profiling of various drug perturbations |
SCIENCE ADVANCES
|
| 2019-03 |
Chimeric crRNAs with 19 DNA residues in the guide region show the retained DNA cleavage activity of Cas9 with potential to improve the specificity |
CHEMICAL COMMUNICATIONS
|
| 2019-03 |
Facilitated Large-Scale Sequence Validation Platform Using Tn5-Tagmented Cell Lysates |
ACS SYNTHETIC BIOLOGY
|
| 2019-03 |
Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements |
NATURE COMMUNICATIONS
|
| 2019-01 |
NFATC3–PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines |
CANCER RESEARCH AND TREATMENT
|
| 2019-01 |
CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system |
NUCLEIC ACIDS RESEARCH
|
| 2018-08 |
Selective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells |
SCIENTIFIC REPORTS
|
| 2018-08 |
Single-cell RNA sequencing technologies and bioinformatics pipelines |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2018-07 |
Straightforward Delivery of Linearized Double-Stranded DNA Encoding sgRNA and Donor DNA for the Generation of Single Nucleotide Variants Based on the CRISPR/Cas9 System |
ACS SYNTHETIC BIOLOGY
|
| 2018-05 |
High-throughput construction of multiple cas9 gene variants via assembly of high-depth tiled and sequence-verified oligonucleotides |
NUCLEIC ACIDS RESEARCH
|
| 2018-04 |
Highly selective retrieval of accurate DNA utilizing a pool of in situ-replicated DNA from multiple next-generation sequencing platforms |
NUCLEIC ACIDS RESEARCH
|
| 2017-10 |
The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians |
LEUKEMIA RESEARCH
|
| 2017-09 |
Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer |
CANCER
|
| 2017-05 |
Asymmetrical barcode adapter-assisted recovery of duplicate reads and error correction strategy to detect rare mutations in circulating tumor DNA |
SCIENTIFIC REPORTS
|
| 2016-12 |
Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs |
JOURNAL OF CONTROLLED RELEASE
|
| 2016-12 |
Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing |
PLOS ONE
|
| 2016-11 |
Toward a new paradigm of DNA writing using a massively parallel sequencing platform and degenerate oligonucleotide |
SCIENTIFIC REPORTS
|
| 2016-09 |
Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer |
ONCOTARGET
|
| 2016-08 |
Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification |
BIOMATERIALS SCIENCE
|
| 2016-08 |
FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas |
ONCOTARGET
|
| 2016-04 |
Nano-formulation of a photosensitizer using a DNA tetrahedron and its potential for in vivo photodynamic therapy |
BIOMATERIALS SCIENCE
|
| 2016-01 |
Clinical and Pathological Heterogeneity of Korean Patients with CAPN3 Mutations |
YONSEI MEDICAL JOURNAL
|
| 2015-09 |
De novo assembly and next-generation sequencing to analyze full-length gene variants from codon-barcoded libraries |
NATURE COMMUNICATIONS
|
| 2015-06 |
Targeted next-generation sequencing for the genetic diagnosis of dysferlinopathy |
NEUROMUSCULAR DISORDERS
|
| 2015-05 |
Genetic testing of korean familial hypercholesterolemia using whole-exome sequencing |
PLOS ONE
|
| 2015-03 |
Repetitive genomic insertion of gene-sized dsDNAs by targeting the promoter region of a counter-selectable marker |
SCIENTIFIC REPORTS
|
| 2015-03 |
microDuMIP: target-enrichment technique for microarray-based duplex molecular inversion probes |
NUCLEIC ACIDS RESEARCH
|
| 2015-02 |
Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing |
BMC CANCER
|
| 2015-02 |
A high-throughput optomechanical retrieval method for sequence-verified clonal DNA from the NGS platform |
NATURE COMMUNICATIONS
|
| 2014-11 |
Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis |
ONCOGENE
|
| 2014-02 |
Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers |
GENOME MEDICINE
|
| 2013-11 |
Genome-scale genetic engineering in Escherichia coli |
BIOTECHNOLOGY ADVANCES
|
| 2013-07 |
The Impact of Cigarette Smoking on the Frequency of and Qualitative Differences in KRAS Mutations in Korean Patients with Lung Adenocarcinoma |
YONSEI MEDICAL JOURNAL
|
| 2013-06 |
Total chemical synthesis of fully functional Photoactive Yellow Protein |
BIOORGANIC & MEDICINAL CHEMISTRY
|
| 2013-03 |
A library of TAL effector nucleases spanning the human genome |
NATURE BIOTECHNOLOGY
|
| 2012-10 |
'Shotgun DNA synthesis' for the high-throughput construction of large DNA molecules |
NUCLEIC ACIDS RESEARCH
|
| 2012-06 |
Genome-scale promoter engineering by coselection MAGE |
NATURE METHODS
|
| 2012-02 |
Design, Total Chemical Synthesis, and X-Ray Structure of a Protein Having a Novel Linear-Loop Polypeptide Chain Topology |
Angewandte Chemie-International Edition
|
| 2011-11 |
Production of Transgenic Bovine Cloned Embryos Using Piggybac Transposition |
JOURNAL OF VETERINARY MEDICAL SCIENCE
|
| 2011-08 |
Use of Model Peptide Reactions for the Characterization of Kinetically Controlled Ligation |
BIOCONJUGATE CHEMISTRY
|
| 2011-08 |
Multiple target loci assembly sequencing (mTAS) |
ANALYTICAL BIOCHEMISTRY
|
| 2011-07 |
Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement |
SCIENCE
|
| 2011-02 |
Hierarchical gene synthesis using DNA microchip oligonucleotides |
JOURNAL OF BIOTECHNOLOGY
|
| 2011-01 |
Surface PEGylation via Native Chemical Ligation |
BIOCONJUGATE CHEMISTRY
|
| 2010-11 |
A Fluorescence Selection Method for Accurate Large-Gene Synthesis |
CHEMBIOCHEM
|
| 2010-06 |
Challenges in the Chemical Synthesis of Average Sized Proteins: Sequential vs. Convergent Ligation of Multiple Peptide Fragments |
BIOPOLYMERS
|
| 2009-05 |
Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide |
Molecular Biosystems
|
| 2008-01 |
Gene synthesis by circular assembly amplification |
Nature Methods
|
| 2006-06 |
Kinetically controlled ligation for the convergent chemical synthesis of proteins |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2006-03 |
Direct On-Resin Synthesis of Peptide-αThiophenylesters for Use in Native Chemical Ligation |
ORGANIC LETTERS
|
| 2006-03 |
Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis |
NATURE CHEMICAL BIOLOGY
|
| 2005-06 |
Total Chemical Synthesis and X-ray Crystal Structure of a Protein Diastereomer: [D-Gln35]Ubiquitin |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2005-04 |
His6 tag-assisted chemical protein synthesis |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2004-05 |
A One-Pot Total Synthesis of Crambin |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2004-01 |
Total Chemical Synthesis of Crambin |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
|